2nd Annual CryoNet Symposium: Postrevolution Cryo-EM: Reaping the benefits while looking to the future
The 2nd Annual CryoNet Symposium brings together leading researchers in cryo-electron microscopy to discuss the latest discoveries and methodological advances in structural biology. This two-day symposium features presentations on protein-nucleic acid complexes, membrane proteins, and cutting-edge developments in cryo-EM technology.
Key Information
- Venue: Biomedicum Lecture Hall, Karolinska Institutet
- Registration: Closed
- Format: 24 talks and 44 poster presentations
- Organizers: Alexey Amunts (Stockholm University), Bridget Carragher (Columbia University, USA), Ausra Domanska (University of Helsinki, Finland), Gunnar von Heijne (Stockholm University)
Theme
"Postrevolution Cryo-EM: Reaping the benefits while looking to the future" - focusing on how the field is capitalizing on recent advances while continuing to push technological boundaries.
Scientific Program Highlights
Day 1 (October 10, 2019)
Morning Sessions:
- Keynote on membrane protein structures and drug discovery
- Advances in single particle cryo-EM methodology
- Novel insights into ribosome structure and function
- Protein-nucleic acid complex structures
Afternoon Sessions:
- Cryo-electron tomography applications
- Time-resolved cryo-EM techniques
- High-resolution structure determination
- Poster Session I (22 posters)
Day 2 (October 11, 2019)
Morning Sessions:
- Structural biology of viral proteins
- Membrane protein complexes
- Methodological advances in sample preparation
- Image processing and reconstruction techniques
Afternoon Sessions:
- Applications to drug discovery
- Structural dynamics and conformational changes
- Integration with other structural biology techniques
- Poster Session II (22 posters)
Featured Speakers
Invited Speakers
- Bridget Carragher (Columbia University, USA) - "The National Resource for Automated Molecular Microscopy (NRAMM)"
- Mavis Agbandje-McKenna (University of Florida, USA) - "AAV vectors for gene delivery applications"
- Hongwei Wang (Tsinghua University, China) - "The calcium homeostasis modulator (CALHM) family of large-pore channels"
- Kristina Djinovic-Carugo (University of Vienna, Austria) - "Structure of the Z-disk and its role in mechanosensing"
- Leo Hanke (Karolinska Institutet) - "Broadly neutralizing antibodies against HIV-1"
- Elizabeth Villa (UC San Diego, USA) - "Exploring the molecular architecture of life in situ with cryo-electron tomography"
- Meindert Lamers (Leiden University, Netherlands) - "Structures of DNA damage tolerance"
- Sebastian Westenhoff (University of Gothenburg) - "Time-resolved serial femtosecond crystallography captures light-driven DNA repair"
- Chris Russo (MRC Laboratory of Molecular Biology, UK) - "Physical principles of specimen behavior in the electron microscope"
Selected Speakers
The symposium features 15 selected talks from submitted abstracts, covering topics including:
- Structural studies of membrane proteins and complexes
- Novel applications of cryo-EM in drug discovery
- Methodological developments in sample preparation and image processing
- Structural insights into cellular processes
- Virus structure and assembly mechanisms
Poster Sessions
44 poster presentations across two sessions, showcasing cutting-edge research from graduate students, postdocs, and research scientists across the Nordic region and beyond. Topics include:
- Novel protein structures
- Methods development
- Sample preparation techniques
- Image processing algorithms
- Applications to disease mechanisms
Practical Information
Transportation
- From Arlanda Airport: Arlanda Express train to Stockholm Central, then public transport
- Public Transport: SL green line to Sankt Eriksplan or bus 3, 6, 70, 77 to Karolinska Institutet
Accommodation
Participants arranged their own accommodation in Stockholm.
WiFi
- Network: Eduroam or KI Guest
- Password provided at registration
Social Program
- Welcome reception: October 9, 2019
- Conference dinner: October 10, 2019
About CryoNet
CryoNet is a Nordic network for cryo-electron microscopy funded by the Knut and Alice Wallenberg Foundation and the Novo Nordisk Foundation. The network connects researchers across Sweden, Denmark, Finland, and Norway to advance the field of structural biology through collaborative research, training, and resource sharing.
Sponsors
- Knut and Alice Wallenberg Foundation
- Novo Nordisk Foundation
- Stockholm University
- Karolinska Institutet
- University of Copenhagen
- University of Helsinki
Contact
For inquiries about past symposium materials, please contact the CryoNet coordination office.
Note: This was the second in a series of annual CryoNet symposiums bringing together the Nordic cryo-EM community. The symposium successfully fostered collaboration and knowledge exchange among researchers at all career stages.